Pandemics & Society Seminar, 9th October: “Mismeasuring pandemics in causal research: Errors, biases, mismatched estimands, ambiguous channels, and the 1918 influenza pandemic”

For the fourth Pandemics & Society Seminar of our Fall 2025 series we are pleased to welcome Hampton Gaddy (London School of Economics & University of Oxford). The seminar will be held on Thursday, 9th October at the normal time (1600 CEST). More information about our speaker and the presentation is below. You can sign up for email notifications about the seminar series, including the Zoom details, here.

Blurb: A large body of social science and health research uses measures of the 1918 influenza pandemic’s mortality to estimate what the biosocial effects of the pandemic were. However, many of the pandemic measures used in this research either exhibit very high rates of error; are systematically correlated with pre-pandemics determinants of the effect of interest; or are a poorly chosen estimand for testing the causal chain of interest. Additionally, even though pandemics have wide-ranging impacts on society, many existing studies do not attempt to rule out plausible alternate channels linking the pandemic to the effect of interest. Each of these four methodological problems can produce false negative results, false positive results, and false positive results of the incorrect sign. We illustrate the extent of these problems using a series of helpful case studies from the 1918 context. In doing so, we make methodological contributions that stress the importance for causal research on pandemic of conducting sensitivity analyses on the calculation of excess mortality, accounting for omitted variable and collider bias, and measuring pandemic severity for the most theoretically appropriate time period and point-of-view.

Biography: Hampton Gaddy is a PhD researcher in demography and economic history at the London School of Economics and an affiliate at the Leverhulme Centre for Demographic Science at the University of Oxford. He works primarily on the 1918 influenza pandemic, the determinants of its mortality, and its social consequences.

New Guest Researcher: Katarina Matthes (University of Zurich)

At PANSOC we have for several years hosted international guest researchers from all over the world. This time we are thrilled to welcome Katarina Matthes from the University of Zurich to Oslo 10-13 October 2025. While at PANSOC, Katarina will present some of her ongoing work and projects (see below) and we will discuss future collaborations.

Katarina Matthes | Institute of Evolutionary Medicine (IEM) | UZH is a senior researcher at the University of Zurich. Her research focuses on past pandemics, particularly influenza, and addresses various dimensions of a pandemic, including immediate effects such as mortality, morbidity, and birth outcomes, as well as long-term health effects due to exposure in-utero or early childhood.

In addition, she investigates social inequalities in mortality trends in Switzerland, where she is currently PI of the SNSF project “Socio-demographic inequalities in the causes of death in Switzerland, 1877–2024.” In this project, individual-level historical causes of death from the city of Zurich (1877 – 1968) are transcribed for the first time in Switzerland. This enables analyses of sociodemographic and socioeconomic differences in mortality over time, as well as in-depth studies of mortality during the 1890 and 1918 influenza pandemics.

Pandemics & Society Seminar, 2nd October: “Fetal Stress during the 1918–1920 Influenza Pandemic: Short- and Long-Term Health Effects in Switzerland”

For the third Pandemics & Society Seminar of our Fall 2025 series we are pleased to welcome Katarina Luise Matthes (University of Zürich). The seminar will be held on Thursday, 2nd October at the normal time (1600 CEST). More information about our speaker and the presentation is below. You can sign up for email notifications about the seminar series, including the Zoom details, here.

Blurb: This talk explores the short and long-term health and mortality effects of the 1918-19 pandemic cohorts. I will first discuss neonatal health during the 1918-19 influenza pandemic in a Swiss city and second the mortality risk across the lifespan. Previous studies have shown that individuals born during the 1918/19 pandemic exhibit reduced life expectancy compared to adjacent birth cohorts. However, the specific causes of death contributing to the elevated mortality risk over the life for those cohorts remain unexplored. This study addresses that gap by decomposing all-cause excess mortality into cause-specific contributions across the lifespan of the 1918-19 pandemic cohorts in Switzerland.

Biography: Katarina Matthes is a senior researcher at the Institute of Evolutionary Medicine, University of Zurich. Her research focuses on past pandemics, particularly influenza, and addresses various dimensions of a pandemic, including immediate effects such as mortality, morbidity, and birth outcomes, as well as long-term health effects due to exposure in utero or early childhood. In addition, she investigates social inequalities in mortality trends in Switzerland, where she is currently PI of the SNSF project “Socio-demographic inequalities in the causes of death in Switzerland, 1877–2024.”

New co-authored paper:

Our Centre leader Mamelund has co-authored a new paper in GeroScience.

You can access the paper here: Cognitive function, physical function, and mental health in older adults amid reduced primary and specialist healthcare service use during COVID-19: the HUNT study | GeroScience

Abstract:

COVID-19 containment measures reduced older adults’ healthcare access, with uncertain long-term effects on cognitive, physical, and mental health. To investigate whether reductions in primary and specialist healthcare service use during the pandemic were associated with changes in cognitive, physical, and mental health in community-dwelling older adults, with attention to sex differences. Data from the Norwegian Trøndelag Health Study collected before (HUNT4 70 + , 2017–2019) and after the pandemic (HUNT AiT, 2021–2023) included 5387 participants (53% women) aged 70 + . Propensity score matching, accounting for baseline confounders, was used to examine associations between reduced healthcare service use and cognitive, physical, and mental health changes from pre- to post-pandemic. Reduced contact with general practitioners was associated with greater cognitive decline among women (MoCa-change − 0.32 [95% CI − 0.62, − 0.32]). No differences were observed in physical or mental health. Reductions in other primary care services (e.g., in-home nursing, practical assistance) were associated with greater decline in cognitive function (MoCa-change − 0.94 [− 1.53, − 0.36]), particularly among men (MoCa-change − 2.12 [− 3.13, − 1.11]). Men also had a decline in physical function (SPPB-change − 1.06 [− 1.79, − 0.33]). No differences in mental health were observed. Reductions in specialist healthcare services were unrelated to health changes in the overall sample but linked to improved physical function in women (SPPB-change 0.32 [0.11, 0.53]). Although associations between reduced healthcare service use during the pandemic and cognitive, physical, and mental health were limited, findings highlight the importance of sustaining access to primary care for older adults during public health crises.

New publication: “The New Syndemic of Obesity and COVID-19 in Urban areas”

Together with two of our prior post-doc’s, Margarida Pereira and Jessica Dimka, our Centre leader S-E Mamelund has written a chapter in a new book: Pandemics and Urban Planning: Multidisciplinary Perspectives on Cities, Planning and Disease | SpringerLink. The book

  • Discusses the potential of urban planning in anticipation and prevention of infectious disease epidemics and pandemics
  • Offers multidisciplinary insights from historical case studies to present issues, and charting pathways into the future
  • Encourages cross-sectoral discussions and integrative policies between urban planning and health fields

Our chapter (chap 10) is titled The New Syndemic of Obesity and COVID-19 in Urban Areas | SpringerLink

Abstract: Soon after the emergence of the COVID-19 pandemic, clinicians and scientists warned that individuals with obesity developed more severe cases of COVID-19, needed more intensive healthcare, and had higher chances of dying. Currently, nearly 40% of the world’s adult population is overweight and 15% has obesity. Obesity rates are higher in urban areas, which were the locations where the first large outbreaks of COVID-19 occurred. However, obesity is more than a risk factor for COVID-19 and addressing it as such underestimates the negative effect of the interaction between both diseases on social, health and gender equity. Obesity prevalence is higher in women, unemployed individuals, and those with lower socioeconomic status. The emergence of this new syndemic adds evidence on how poor health outcomes tend to cluster spatially and increase health inequities, particularly in urban areas. Hence, urban planning plays an important role in preventing social, health, and gender disparities. The ability to create healthier urban configurations for all is an important means to protect vulnerable populations and urban neighbourhoods during a pandemic. An equity lens is needed to address the major planning, namely land use, mobility, accessibility, and housing, as a strategy to tackle this new syndemic.

Pandemics & Society Seminar, 25 September: “Labour Scarcity and Productivity: Insights from the Last Nordic Plague”

For the second Pandemics & Society Seminar of our Fall 2025 series we are pleased to welcome Max Marczinek (University of Oxford). The seminar will be held on Thursday, 25 September at the normal time (1600 CEST). More information about our speaker and the presentation is below. You can sign up for email notifications about the seminar series, including the Zoom details, here.

Blurb: In this webinar, Marczinek will present a paper studying the relationship between labour scarcity and productivity in the context of a 1710s plague outbreak. While higher wages should have led to an export contraction, exports grew after plagued regions shifted into capital-intensive production. Using a Ricardian model, he show that productivity growth in capital-intensive sectors is best suited to explain this export boom. Marczinek argue that labour scarcity incentivises capital-intensive production which raises productivity growth.

Biography: Max Marczinek is a 4th year PhD student in Economics at Oxford University. His research studies trade, labour, and economic history. He combine trade models with novel and often historical data sources, using theory to extract new insights from granular data.

Pandemics & Society Seminar, 18 September: “Survivors: The psychological impact of the Black Death on economic performance”.

For the first Pandemics & Society Seminar of our Fall 2025 series we are pleased to welcome Robert Braid (University of Montpellier). The seminar will be held on Thursday, 18 September at the normal time (1600 CEST). More information about our speaker and the presentation is below. You can sign up for email notifications about the seminar series, including the Zoom details, here.

Abstract: This paper integrates the findings of psychology and behavioral economics in order to understand better an historical phenomenon. After the Black Death, a plague epidemic which wiped out roughly 40% of the population, the historical data runs counter to all economic theory that would predict an increase in productivity and higher real wages. Peasants inherited the most fertile lands and had larger farms, yet grain yields fell. Capital (tools, windmills, livestock, carts, etc.) per capita increased tremendously but productivity fell. Commercial infrastructure and public administration remained intact, but trade dropped off. There was an acute shortage of labour yet real wages stagnated. Although climate factors may account for some of these trends, they don’t explain all, leaving economic historians of this period perplexed. This study argues that the Black Death caused trauma in survivors, altering levels of biochemicals leading to increased agitation and lack of attention in some and disengagement in others, similar to the behavior of victims of PTSD. Chroniclers and other observers recorded a number of behavior patterns among survivors which suggest that the Black Death was a deeply traumatic event which affected their ability to work. These findings are also consistent with the historical data on productivity and may also shed light on the increased levels of civil unrest in the post-plague era.

Biography: Robert Braid is Assistant Professor at the Faculty of Economics of the University of Montpellier (France), and member of the Center for Environmental Research – Montpellier. He focuses on the origins of economic regulations across different western European regions, in particular in the 13th and 14th centuries. Most of his work has been dedicated to understanding the psychological, social and economic impact of the Black Death which gave rise to a broad wave of unprecedented economic regulations seeking to constrain the demands of workers and retailers. He has also worked on the medieval scholastic literature that attempts to give a moral framework both for economic agents and for rulers who seek to regulate their behavior, and how this literature changed soon after the plague. He has also worked on wage theory and the history of economic thought in general. 

Fall 2025 seminar series

We are pleased to release the schedule for our Fall 2025 seminar series. As in previous series, the seminar will be held via Zoom at 16.00 Central European Time on Thursdays.

To access the Zoom meetings, please join our mailing list here.

18 September: Robert Braid (University of Montpellier), Survivors: The psychological impact of the Black Death on economic performance.

25 September: Max Marczinek (University of Oxford), Labour Scarcity and Productivity: Insights from the Last Nordic Plague.

2 October: Katarina Luise Matthes (University of Zürich), Fetal Stress during the 1918–1920 Influenza Pandemic: Short- and Long-Term Health Effects in Switzerland.

9 October: Hampton Gaddy (London School of Economics), Mismeasuring pandemics in causal research: Errors, biases, mismatched estimands, ambiguous channels, and the 1918 influenza pandemic.

30 October: Florian Bonnet (INED), Contextualizing the Global Burden of COVID-19 Pandemic: A Historical and Geographical Exploration of Excess Mortality in France, 1901–2021.

6 November: Christoph Gradmann (University of Oslo), An Invisible Epidemic: Studying Tuberculosis in Interwar Tanganyika.

13 November: Andrea Kifyasi (University of Dar es Salaam), From China to Africa: A History of the 1957 Asian Influenza Pandemic in Colonial Tanganyika.

20 November: Sheilagh Ogilvie (University of Oxford), Controlling Contagion: Epidemics and Institutions from the Black Death to Covid.

4 December: Abigail Dumes (University of Michigan), Long COVID as Disability in Higher Education.
**Postponed until Spring 2026**

11 December: Mallika Snyder (University of California, Berkeley), Who Will Remember COVID-19? Kinship Memory after a Global Pandemic.

New Paper: Inclusion of Deprivation in Endemic-Epidemic Models

Deprivation amplification theory suggests that the health effects of individual deprivation are amplified for people who live in areas with greater levels of deprivation. In a new paper in Vienna Yearbook of Population Research, first authored by former PANSOC post-doc, Maria Bekker-Nielsen Dunbar, we postulate that health (represented by norovirus incidence) is influenced and amplified by deprivation (a measure that includes socio-economic factors), and believe that this association has been neglected in surveillance models of infectious diseases. We construct a social epidemiological extension of a known surveillance model to evaluate the inclusion of deprivation in surveillance models using the German Index of Socio-economic Deprivation (GISD) in an endemic-epidemic model. We evaluate model types considered in the literature on the basis of Akaike’s information criterion. Our results suggest that a social epidemiological endemic-epidemic model with the GISD for enterically transmitted infections does not need to also include time-varying contact matrices as transmission weights.

You can read the paper here: Vienna Yearbook of Population Research 2025